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(−)-Myrtenal (Synonyms: (1R)-(-)-桃金娘烯醛; (1R)-(−)-Myrtenal; (−)-(1R,5S)-Myrtenal) 纯度: 96.94%
(−)-Myrtenal ((1R)-(−)-Myrtenal) 是一种口服有效的萜烯,具有抗肿瘤活性。(−)-Myrtenal通过在糖尿病大鼠的骨骼肌和肝脏中通过 Akt 增强 GLUT2 来改善高血糖症。
(−)-Myrtenal Chemical Structure
CAS No. : 18486-69-6
规格 | 价格 | 是否有货 | 数量 |
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500 mg | ¥350 | In-stock | |
1 g | ¥560 | In-stock | |
5 g | 询价 | ||
10 g | 询价 |
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(−)-Myrtenal 相关产品
•相关化合物库:
- Natural Product Library Plus
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- Diabetes Related Compound Library
- Terpenoids Library
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- Traditional Chinese Medicine Monomer Library
生物活性 |
(−)-Myrtenal ((1R)-(−)-Myrtenal) is an orally active terpene with antitumour activity. (−)-Myrtenal ameliorates hyperglycemia by enhancing GLUT2 through Akt in the skeletal muscle and liver of diabetic rats[1][2]. |
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体外研究 (In Vitro) |
(−)-Myrtenal ((1R)-(−)-Myrtenal; 0.1-5 mM; for 24 h) exerts strong cytotoxic effect (IC50 = 5.3 mM) on human colon tumour (HT29) and human normal colon epithelial cells (CCD 841 CoTr)[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
(−)-Myrtenal ((1R)-(−)-Myrtenal; orally; 80 mg/kg/day for 28 days) reveals decreased the levels of plasma glucose, improved the plasma insulin levels, up-regulation of IRS2, Akt and GLUT2 in liver and IRS2, Akt and GLUT4 protein expression in skeletal muscle in diabetic rats induced by single intraperitoneal injection of Streptozotocin (STZ) (40 mg/kg bw)[2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
150.22 |
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Formula |
C10H14O |
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CAS 号 |
18486-69-6 |
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中文名称 |
(1R)-(-)-桃金娘烯醛 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-20°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (665.69 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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