Peptide 74

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Peptide 74  纯度: 98.07%

Peptide 74 是一种合成肽，含有基质金属蛋白酶 (MMP) 的前域序列。Peptide 74 在体外抑制活化形式的 72-kDa IV 型胶原酶。

Peptide 74

Peptide 74 Chemical Structure

CAS No. : 132116-39-3

规格 价格 是否有货 数量
5 mg ￥800 In-stock
10 mg ￥1300 In-stock
25 mg ￥2600 In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Peptide 74 相关产品

•相关化合物库:

  • Bioactive Compound Library Plus
  • Peptide Library

生物活性

Peptide 74 is a synthetic peptide containing the prodomain sequence of matrix metalloproteinase (MMP). Peptide 74 inhibits the activated form of the 72-kDa type IV collagenase in vitro[1].

体外研究
(In Vitro)

Peptide 74 (30 μM) reduces both A2058 and HT 1080 tumor cell invasion by 60-80%[1].
Peptide 74 (30 μM) shows no cytotoxic action and does not inhibit chemotaxis or affect HT1080 and A2058 human tumor cells number[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1558.79

Formula

C62H107N23O20S2
CAS 号

132116-39-3
Sequence Shortening

TMRKPRCGNPDVAN
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶解性数据
In Vitro: 

H2O : 100 mg/mL (64.15 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.6415 mL 3.2076 mL 6.4152 mL
5 mM 0.1283 mL 0.6415 mL 1.2830 mL
10 mM 0.0642 mL 0.3208 mL 0.6415 mL

*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。
参考文献

  • [1]. A Melchiori, et al. Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment. Cancer Res. 1992 Apr 15;52(8):2353-6.

    [2]. P P Lee, et al. Functional role of matrix metalloproteinases (MMPs) in mammary epithelial cell development. J Cell Physiol. 2001 Jul;188(1):75-88.

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