SPOP-IN-6b hydrochloride | whatman (沃特曼)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

SPOP-IN-6b hydrochloride

SPOP-IN-6b hydrochloride 是一种有效的斑型 POZ 蛋白 (SPOP) 抑制剂，IC₅₀ 为 3.58 μM。

SPOP-IN-6b hydrochloride Chemical Structure

CAS No. : 2136270-68-1

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SPOP-IN-6b hydrochloride 的其他形式现货产品:

SPOP-IN-6b SPOP-IN-6b dihydrochloride

生物活性	SPOP-IN-6b hydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC₅₀ of 3.58 μM^[1].
体外研究 (In Vitro)	SPOP-IN-6b shows IC₅₀s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2 and 786-0 cells^[1]. SPOP-IN-6b (0.1-3.0 μM; 10 hours) can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN and DUSP7 content^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究 (In Vivo)	SPOP-IN-6b (40-80 mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) can slow down the growth of tumour by suppressing SPOP^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	537.05
Formula	C₂₈H₃₃ClN₆O₃
CAS 号	2136270-68-1
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Guangcai Y, et al. The pyrido-pyrimidines of 2- imines -5- ketone group -2,5- dihydros -1-H- two. CN107141287A.

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