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(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH (Synonyms: VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH) 纯度: 99.31%
(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH (VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH) 是一种 E3 连接酶配体-linker 偶联物 (E3 ligase ligand-linker conjugate) ,包含 VHL 配体。
![(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH Chemical Structure (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH(Synonyms: VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH)](http://www.fluoroprobe.com/wp-content/uploads/2022/05/hy-131168.gif)
(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH Chemical Structure
CAS No. : 2086301-47-3
规格 | 价格 | 是否有货 | 数量 |
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10 mg | ¥8000 | In-stock | |
25 mg | ¥15500 | In-stock | |
50 mg | 询价 | ||
100 mg | 询价 |
* Please select Quantity before adding items.
生物活性 |
(S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH (VH032-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH) is a E3 ligase ligand-linker conjugate that contains on one end a VHL ligand. (S,R,S)-AHPC-Boc-trans-3-aminocyclobutanol-Pip-CH2COOH is used in PROTAC technology[1]. |
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IC50 & Target[1] |
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体外研究 (In Vitro) |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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分子量 |
754.98 |
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Formula |
C39H58N6O7S |
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CAS 号 |
2086301-47-3 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
-20°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
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溶解性数据 |
In Vitro:
DMSO : 100 mg/mL (132.45 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
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参考文献 |
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