上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
myo-Inositol trispyrophosphate hexasodium (Synonyms: ITPP hexasodium)
myo-Inositol trispyrophosphate (ITPP) hexasodium 是血红蛋白 (haemoglobin) 调节剂,是一种变构效应物,可降低血红蛋白的氧结合亲和力并促进红细胞释放氧。myo-Inositol trispyrophosphatehexasodium 可以逆转缺氧,控制肿瘤生长并改善化疗反应。
myo-Inositol trispyrophosphate hexasodium Chemical Structure
CAS No. : 23103-35-7
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生物活性 |
myo-Inositol trispyrophosphate (ITPP) hexasodium, a modifier of haemoglobin, is an allosteric effector that reduces the oxygen‐binding affinity of haemoglobin and facilitates the release of oxygen by red blood cells. myo-Inositol trispyrophosphate can reverse hypoxia, control tumor growth and improve chemotherapy response[1][2][3]. |
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体外研究 (In Vitro) |
myo-Inositol trispyrophosphate hexasodium (10 mmol/L; 2 hours) significantly inhibits OCR in all six cell lines (FSaII, SiHa, MDA‐MB‐231, NT2, 9L‐glioma and rhabdomyosarcoma) [2]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
myo-Inositol trispyrophosphate hexasodium (2 g/kg weekly; IP; 7weeks) sustains its significant effect on life prolongation[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
737.88 |
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Formula |
C6H6Na6O21P6 |
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CAS 号 |
23103-35-7 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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