上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
IRES-C11
IRES-C11 是一种特异的 c-MYC 内部核糖体进入位点 (IRES) 翻译抑制剂。IRES-C11 阻断必需的 c-MYC IRES 反式作用因子、异质核核糖核蛋白 A1 与其 IRES 的相互作用。IRES-C11 不抑制 BAG-1、XIAP 和 p53 IRESes。
IRES-C11 Chemical Structure
CAS No. : 342416-30-2
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100 mg | 询价 | ||
250 mg | 询价 | ||
500 mg | 询价 |
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生物活性 |
IRES-C11 is a spectfic c-MYC internal ribosome entry site (IRES) translation inhibitor. IRES-C11 blocks the interaction of a requisite c-MYC IRES trans-acting factor, heterogeneous nuclear ribonucleoprotein A1, with its IRES. IRES-C11 does not inhibits BAG-1, XIAP and p53 IRESes[1][2]. |
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体外研究 (In Vitro) |
IRES-C11 blocks cyclin D1 IRES-dependent initiation and demonstrates synergistic anti-glioblastoma properties when combined with the mechanistic target of mTOR PP242[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
316.14 |
Formula |
C13H11Cl2NO4 |
CAS 号 |
342416-30-2 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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