Hippeastrine(Synonyms: 小星蒜碱)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Hippeastrine (Synonyms: 小星蒜碱)

Hippeastrine 是一种活性生物碱，对拓扑异构酶 I Top I 具有良好的剂量依赖性抑制作用，IC50 为7.25 μg/mL。具有抗增殖和抗癌活性。

Hippeastrine(Synonyms: 小星蒜碱)

Hippeastrine Chemical Structure

CAS No. : 477-17-8

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

Hippeastrine, an active alkaloid, exhibits a good dose-dependent inhibitory effect against topoisomerase I (Top I) with an IC50 at 7.25 μg/mL. Antiproliferative and anticancer activities[1].

体外研究
(In Vitro)

Hippeastrine strongly inhibits the proliferation of HT-29 and Hep G2 cells in an intuitive dose-dependent manner with the IC50s at 3.98 μg/mL and 11.85 μg/mL, respectively, and also induces significant cellular morphological changes, which further validate our screening method and the potent antineoplastic effects[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

315.32

Formula

C17H17NO5
CAS 号

477-17-8
中文名称

小星蒜碱
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Chen GL, et al. Antiproliferative activities of Amaryllidaceae alkaloids from Lycoris radiata targeting DNA topoisomerase I. Sci Rep. 2016;6:38284. Published 2016 Dec 6.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务