Retrorsine N-oxide

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Retrorsine N-oxide 

Retrorsine N-oxide 是吡咯联啶生物碱的一种 N-氧化物，是一种致癌物。Retrorsine N-oxide 衍生的 DNA 加合物是吡咯里西啶生物碱 N-氧化物的常见毒理学生物标记物。

Retrorsine N-oxide

Retrorsine N-oxide Chemical Structure

CAS No. : 15503-86-3

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

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生物活性

Retrorsine N-oxide, an N-oxide of pyrrolizidine alkaloid, is a carcinogen. Retrorsine N-oxide-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides[1][2].

体内研究
(In Vivo)

Retrorsine N-oxide produces DNA adducts, the common biological biomarker of PA-induced liver tumor formation[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

367.39

Formula

C18H25NO7
CAS 号

15503-86-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. He X, et, al. Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides. J Food Drug Anal. 2017 Oct;25(4):984-991.

    [2]. Valese AC, et, al. Quantification of pyrrolizidine alkaloids in Senecio brasiliensis, beehive pollen, and honey by LC-MS/MS. J Environ Sci Health B. 2021;56(7):685-694.

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