上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
6-Hydroxy-DOPA
6-Hydroxy-DOPA 是一种选择性和有效的 RAD52 ssDNA 结合域的变构抑制剂。6-Hydroxy-DOPA 可用于癌症研究。
6-Hydroxy-DOPA Chemical Structure
CAS No. : 21373-30-8
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100 mg | 询价 | ||
250 mg | 询价 | ||
500 mg | 询价 |
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生物活性 |
6-Hydroxy-DOPA is a selective and effective allosteric inhibitor of the RAD52 ssDNA binding domain. 6-Hydroxy-DOPA can be used for the research of cancer[1]. |
IC50 & Target |
RAD52[1] |
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体外研究 (In Vitro) |
6-Hydroxy-DOPA (0~20 μM; U20S cells) selectively inhibits RAD52-mediated recombination. 6-Hydroxy-DOPA (0~10 μM; HEK293T cells) decreases the number of eGFP-RAD52 foci in a dose-dependent manner. 6-Hydroxy-DOPA (5~75 μM; HCC1937 cells) selectively reduces the viability of the BRCA1-deficient triple-negative breast cancer cell line HCC1937[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
213.19 |
Formula |
C9H11NO5 |
CAS 号 |
21373-30-8 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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