Migrastatin is a typical Fascin1 inhibitor. Migrastatin is isolated from a cultured broth of Streptomyces sp. MK929-43F1. Migrastatin inhibits tumor cell migration^[1][2].

Fascin1^[1]

Migrastatin (100 μM) leads to the disorganization of the bundles. Migrastatin (100 μM; HCT-116 and DLD-1 cells) prevents cell migration^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

489.60

C₂₇H₃₉NO₇

314245-65-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Montoro-García S, et al. Novel anti-invasive properties of a Fascin1 inhibitor on colorectal cancer cells. J Mol Med (Berl). 2020;98(3):383-394.

  [2]. Nakae K, et al. Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo). 2000;53(10):1130-1136.