(+)-Syringaresinol(Synonyms: (+)-丁香树脂酚)

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(+)-Syringaresinol (Synonyms: (+)-丁香树脂酚)

(+)-Syringaresinol，一种木脂素，是 NFAT 转录因子抑制剂，IC50 值为 329.4 μM。(+)-Syringaresinol 也可用于淋巴细胞白血病的研究。

(+)-Syringaresinol(Synonyms: (+)-丁香树脂酚)

(+)-Syringaresinol Chemical Structure

CAS No. : 21453-69-0

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生物活性

(+)-Syringaresinol, a lignan, is a NFAT transcription factor inhibitor, with an IC50 of 329.4 μM. (+)-Syringaresinol also can be used for the research of lymphocytic leukemia[1][2].

IC50 & Target

IC50: 329.4 μM (NFAT transcription factor)[1]
体外研究
(In Vitro)

(+)-Syringaresinol inhibits the growth of P-388 cells, with an ED50 0.41 μg/mL[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

418.44

Formula

C22H26O8
CAS 号

21453-69-0
中文名称

(+)-丁香树脂酚
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Cai XF, et, al. Inhibitory lignans against NFAT transcription factor from Acanthopanax koreanum. Arch Pharm Res. 2004 Jul;27(7):738-41.

    [2]. Badawi MM, et, al. Plant anticancer agents XXVII: Antileukemic and cytotoxic constituents of Dirca occidentalis (Thymelaeaceae). J Pharm Sci. 1983 Nov;72(11):1285-7.

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