Thailanstatin C

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Thailanstatin C 

Thailanstatin C 是一种 pre-mRNA 剪接 (pre-mRNA splicing) 抑制剂 (IC50= 6.84 μM)，也是一种抗增殖剂。

Thailanstatin C

Thailanstatin C Chemical Structure

CAS No. : 1426953-24-3

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生物活性

Thailanstatin C is a pre-mRNA splicing inhibitor (IC50= 6.84 μM) and antiproliferative agent from Burkholderia thailandensis MSMB43[1].

体外研究
(In Vitro)

Thailanstatin C inhibits human cancer cell lines with IC50s of 2.98-8.82 nM for DU-145, NCI-H232A, MDA-MB-231 and SKOV-3 cells[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

600.14

Formula

C30H46ClNO9
CAS 号

1426953-24-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Liu X, et al. Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43. J Nat Prod. 2013;76(4):685-693.

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