PSMA-ALB-56

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

PSMA-ALB-56 

PSMA-ALB-56 是一种 PSMA-targeting 放射性配体，由谷氨酸-尿素 PSMA-binding 实体和白蛋白结合物构成。

PSMA-ALB-56

PSMA-ALB-56 Chemical Structure

CAS No. : 2306049-48-7

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生物活性

PSMA-ALB-56 is a PSMA-targeting radioligand designed by combining the glutamate-urea PSMA-binding entity and an albumin binder[1].

IC50 & Target

Traditional Cytotoxic Agents

 

体内研究
(In Vivo)

PSMA-ALB-56 accumulates much faster in tumor tissues and is more efficiently cleared from the blood and background tissues, which results in excellent tumor-to-background contrast already 4 hours after injection. PSMA-ALB-56 increases median survival in mice[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1330.52

Formula

C66H95N11O18
CAS 号

2306049-48-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Umbricht CA, et al. Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties To Improve Prostate Cancer Therapy. Mol Pharm. 2018;15(6):2297-2306.

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