Atrovastatin-PEG3-FITC

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Atrovastatin-PEG3-FITC 

Atorvastatin-PEG3-FITC (compound S31) 是一种 KRAS-PDEδ 相互作用抑制剂。Atorvastatin-PEG3-FITC 在荧光各向异性测定中可以充当配体。

Atrovastatin-PEG3-FITC

Atrovastatin-PEG3-FITC Chemical Structure

CAS No. : 1440755-31-6

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生物活性

Atrovastatin-PEG3-FITC (compound S31) is a KRAS-PDEδ interaction inhibitor. Atrovastatin-PEG3-FITC acts as a ligand in fluorescence anisotropy assay[1][2].

IC50 & Target[1]

KRAS-PDEδ

 

分子量

1150.31

Formula

C64H68FN5O12S
CAS 号

1440755-31-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Gunther Zimmermann, et al. Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signaling. Nature. 2013 May 30;497(7451):638-42.

    [2]. Yan Jiang, et al. Structural Biology-Inspired Discovery of Novel KRAS-PDEδ Inhibitors. J Med Chem. 2017 Nov 22;60(22):9400-9406.

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