8-Oxocoptisine(Synonyms: 8-氧黄连碱)

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8-Oxocoptisine (Synonyms: 8-氧黄连碱)

8-Oxocoptisine 是一种天然原小檗碱生物碱,具有抗癌活性。

8-Oxocoptisine(Synonyms: 8-氧黄连碱)

8-Oxocoptisine Chemical Structure

CAS No. : 19716-61-1

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生物活性

8-Oxocoptisine is a natural protoberberine alkaloid with anti-cancer activity[1].

体外研究
(In Vitro)

8-Oxocoptisine has cytotoxicity against NCI-N87 (IC50=20.31 μM) and has no cytotoxicity against Caco-2 (IC50>100 μM)[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

335.31

Formula

C19H13NO5

CAS 号

19716-61-1

中文名称

8-氧黄连碱;8-氧代黄连碱

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

参考文献
  • [1]. Ping Qian, et al. Five new alkaloids from Coptidis Rhizoma-Euodiae Fructus couple and their cytotoxic activities against gastrointestinal cancer cells. Fitoterapia. 2014 Mar;93:74-80.

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