Seco-DUBA hydrochloride

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Seco-DUBA hydrochloride 

Seco-DUBA hydrochloride 是 ADC药物 SYD985 的毒素分子。

Seco-DUBA hydrochloride

Seco-DUBA hydrochloride Chemical Structure

CAS No. : 1795733-93-5

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Seco-DUBA hydrochloride 的其他形式现货产品:

Seco-DUBA

生物活性

Seco-DUBA hydrochloride is a toxin for ADC drug SYD985[1].

Formula

C29H23ClN4O4.xHCl
CAS 号

1795733-93-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
溶解性数据
In Vitro: 

DMSO : 12.5 mg/mL (ultrasonic and warming and heat to 60°C)
参考文献

  • [1]. Ronald C Elgersma, et al. Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody-Drug Conjugate SYD985. Mol Pharm. 2015 Jun 1;12(6):1813-35.

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