FTO-IN-1

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

FTO-IN-1 

FTO-IN-1 是一种脂肪和肥胖相关酶 (FTO) 抑制剂，IC50 值 <1 μM。FTO-IN-1 可用于癌症的研究。详细信息请参考专利文献 WO2018157843A1 中的化合物 32。

FTO-IN-1

FTO-IN-1 Chemical Structure

CAS No. : 2243944-92-3

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FTO-IN-1 的其他形式现货产品:

FTO-IN-1 TFA

生物活性

FTO-IN-1 is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC50 of <1 μm. fto-in-1 can be used for the research of cancer[1].

IC50 & Target

IC50: <1 μm (fto)[1]
体外研究
(In Vitro)

FTO-IN-1 (50 μM) inhibits FTO enzyme activity by 62% in vitro[1].
FTO-IN-1 (50 μM) inhibits the viability of SCLC-21H, RH30 and KP3 cells, with IC50s of 2.1 μM, 5.3 μM, and 5.6 μM, respectively[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

391.25

Formula

C18H16Cl2N4O2
CAS 号

2243944-92-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Yang C, et, al. 2-(substituted benzene matrix) aromatic formate fto inhibitor, preparation method therefor, and applications thereof. WO2018157843A1.

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