Sel-green

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

Sel-green 

Sel-green 是一种选择性的硒醇荧光探针,用于定量硒酶硫氧蛋白还原酶中的 Sec 含量,并对活细胞中的 Sec 进行荧光呈像。

Sel-green

Sel-green Chemical Structure

CAS No. : 1574299-37-8

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5 mg ¥3500 询问价格 & 货期
10 mg ¥5800 询问价格 & 货期

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生物活性

Sel-green, a selective selenol fluorescent probe, is applied to quantify the Sec content in the selenoenzyme thioredoxin reductase and image endogenous Sec in live HepG2 cells[1].

体外研究
(In Vitro)

Sel-green displays >20-fold selectivity of Sec over DTT[1]. Sel-green is suitable for identifying the selenol species metabolized from various selenocompounds in cells, which helps to clarify the mechanism underlying the cytotoxicity of different selenocompounds[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

462.43

Formula

C19H18N4O8S

CAS 号

1574299-37-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

溶解性数据
In Vitro: 

DMSO : 50 mg/mL (108.12 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.1625 mL 10.8124 mL 21.6249 mL
5 mM 0.4325 mL 2.1625 mL 4.3250 mL
10 mM 0.2162 mL 1.0812 mL 2.1625 mL

参考文献
  • [1]. Baoxin Zhang, et al. Selective selenol fluorescent probes: design, synthesis, structural determinants, and biological applications. J Am Chem Soc. 2015 Jan 21;137(2):757-69.

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