上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
PAO-Nap
PAO-Nap 是NAP (naphthalimide) 荧光基团修饰的 PAO。PAO 通过选择性靶向硫氧蛋白还原酶诱导 HL-60 细胞氧化应激介导的凋亡。
PAO-Nap Chemical Structure
CAS No. : 1613402-20-2
| 规格 | 价格 | 是否有货 | |
|---|---|---|---|
| 5 mg | ￥3000 | 询问价格 & 货期 | |
| 10 mg | ￥4800 | 询问价格 & 货期 | |
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| 生物活性 |
PAO-Nap is the modified PAO attached a naphthalimide fluorophore using aminocaproic acid as a linker. PAO induces oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase[1]. |
|---|---|
| 体外研究 (In Vitro) |
PAO exhibits IC50 values of 6.2 μM, 9.4 μM, 7.7 μM in HL-60, 7721 and Hela cells (48 h)[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
509.39 |
| Formula |
C24H24AsN3O5 |
| CAS 号 |
1613402-20-2 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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