Biotin-C4-amide-C5-NH2

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Biotin-C4-amide-C5-NH2 

Biotin-C4-amide-C5-NH2 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

Biotin-C4-amide-C5-NH2

Biotin-C4-amide-C5-NH2 Chemical Structure

CAS No. : 151294-96-1

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生物活性

Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

314.45

Formula

C14H26N4O2S
CAS 号

151294-96-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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