NH2-PEG5-C6-Cl hydrochloride

发表于由

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NH2-PEG5-C6-Cl hydrochloride 

NH2-PEG5-C6-Cl hydrochloride 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

NH2-PEG5-C6-Cl hydrochloride

NH2-PEG5-C6-Cl hydrochloride Chemical Structure

CAS No. : 2241669-16-7

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生物活性

NH2-PEG5-C6-Cl hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

392.36

Formula

C16H35Cl2NO5
CAS 号

2241669-16-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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