上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
Bobcat339
Bobcat339 是一种有效的、选择性的基于胞嘧啶的 TET 酶抑制剂，抑制 TET1 和 TET2 的 IC50 值分别为 33 μM 和 73 μM。Bobcat339 可用于表观遗传学领域研究，并且可作为靶向 DNA 甲基化和基因转录新疗法的起点。
Bobcat339 Chemical Structure
CAS No. : 2280037-51-4
| 规格 | 是否有货 | ||
|---|---|---|---|
| 100 mg | 询价 | ||
| 250 mg | 询价 | ||
| 500 mg | 询价 |
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Bobcat339 的其他形式现货产品:
| 生物活性 |
Bobcat339 is a potent and selective cytosine-based inhibitor of TET enzyme, with IC50s of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription[1]. |
IC50 & Target |
IC50: 33 μM (TET1); 73 μM (TET2)[1] |
|---|---|
| 体外研究 (In Vitro) |
Bobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
| 分子量 |
297.74 |
| Formula |
C16H12ClN3O |
| CAS 号 |
2280037-51-4 |
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
| 参考文献 |
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