CLR1501

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

CLR1501 

CLR1501 是荧光标记的、CLR1404 的类似物，是具有癌细胞选择性的细胞荧光标记物。

CLR1501

CLR1501 Chemical Structure

CAS No. : 1250963-36-0

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生物活性

CLR1501, a fluorescently labeled CLR1404 analog, is a cancer cell-selective fluorescence compound[1][2].

体外研究
(In Vitro)

CLR1501 exhibits five- to ninefold preferential uptake in these cancer cell lines in vitro compared to normal fibroblasts[1].
Excitation/emission peaks are 500/517 nm for CLR1501. CLR1501 exhibits tumor selectivity in vitro and in vivo for human glioblastoma stem-like (GSC) cell lines and xenografts[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

701.67

Formula

C38H59BF2N3O4P
CAS 号

1250963-36-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Weichert JP, et al. Alkylphosphocholine analogs for broad-spectrum cancer imaging and therapy. Sci Transl Med. 2014 Jun 11;6(240):240ra75.

    [2]. Swanson KI, et al. Fluorescent cancer-selective alkylphosphocholine analogs for intraoperative glioma detection. Neurosurgery. 2015 Feb;76(2):115-23; discussion 123-4.

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