上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Tubulin inhibitor 8
Tubulin inhibitor 8 (Compound 33b) 是一种微管蛋白 (tubulin) 抑制剂,也是多种肿瘤细胞系的有效抑制剂。Tubulin inhibitor 8 抑制微管蛋白聚合,IC50 为 0.73 μM。Tubulin inhibitor 6 抑制 K562 细胞生长,IC50 为 14 nM。
Tubulin inhibitor 8 Chemical Structure
CAS No. : 1309925-39-0
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生物活性 |
Tubulin inhibitor 8 (Compound 33b) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. Tubulin inhibitor 8 inhibits tubulin polymerization with an IC50 of 0.73 μM. Tubulin inhibitor 8 inhibits K562 cell growth with an IC50 of 14 nM[1]. |
IC50 & Target |
IC50: 0.73 μM (tubulin polymerization)[1] |
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体外研究 (In Vitro) |
Tubulin inhibitor 8 blocks mitosis through an arrest of cells in the G2/M phase, as illustrated in typical histograms[1]. 上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
342.35 |
Formula |
C21H14N2O3 |
CAS 号 |
1309925-39-0 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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