Z-LE(OMe)TD(OMe)-FMK

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Z-LE(OMe)TD(OMe)-FMK 

Z-LE(OMe)TD(OMe)-FMK 是一种选择性的 caspase-8 抑制剂，可以抑制细胞凋亡。

Z-LE(OMe)TD(OMe)-FMK

Z-LE(OMe)TD(OMe)-FMK Chemical Structure

CAS No. : 210344-93-7

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生物活性

Z-LE(OMe)TD(OMe)-FMK is a selective caspase-8 inhibitor. Z-LE(OMe)TD(OMe)-FMK can inhibit cell apoptosis[1].

体外研究
(In Vitro)

The apoptotic pathway activated after exposure of HL-60 cells to Cordycepin is caspase-8 dependent, because Z-LE(OMe)TD(OMe)-FMK partly inhibits endonucleosomal cleavage of DNA induced by cordycepin alone[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

654.68

Formula

C30H43FN4O11
CAS 号

210344-93-7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Hellinida Thomadaki, et al. The role of cordycepin in cancer treatment via induction or inhibition of apoptosis: implication of polyadenylation in a cell type specific manner. Cancer Chemother Pharmacol. 2008 Feb;61(2):251-65.

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