SENP1-IN-4 | whatman (沃特曼)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

SENP1-IN-4

SENP1-IN-4 是特异性去 SUMO 化蛋白酶 SENP1 的抑制剂，详细请参考专利文献 CN110627860，化合物 21。SENP1-IN-4 被开发用于增强肿瘤放射敏感性。

SENP1-IN-4 Chemical Structure

CAS No. : 2416910-64-8

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性

SENP1-IN-4 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 21. SENP1-IN-4 is developed for tumor radiosensitivity enhancement^[1].

体外研究
(In Vitro)

SENP1-IN-4 improves the sensitivity of tumor cells to irradiation^[1].
SENP1-IN-4 (0.7-20 μM; 72 hours) has cytotoxic for Hella cells with an IC₅₀ of >20 μM^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:	Hela cells
Concentration:	0.7 μ M, 2.2 μM, 6.6 μM、20 μM
Incubation Time:	72 hours
Result:	IC₅₀>20 μM

分子量

526.79

Formula

C₃₃H₅₄N₂O₃

CAS 号

2416910-64-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Li, Yiliang, et al. Preparation of ursolic acid derivatives useful as SENP1 inhibitors and tumor radiosensitizer. CN110627860A.

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