PTZ-343(Synonyms: 3-(10′-Phenothiazinyl)propane-1-sulfonate sodium; SPTZ sodium)

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PTZ-343 (Synonyms: 3-(10′-Phenothiazinyl)propane-1-sulfonate sodium; SPTZ sodium)

PTZ-343 是鲁米诺 (HY-15922) 的强效发光增强剂 (enhancer)。PTZ-343 大大提高了过氧化物酶催化的鲁米诺化学发光氧化反应 (>80%) 的光输出。

PTZ-343(Synonyms: 3-(10′-Phenothiazinyl)propane-1-sulfonate sodium; SPTZ sodium)

PTZ-343 Chemical Structure

CAS No. : 101199-38-6

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生物活性

PTZ-343 is a potent enhancer of Luminol (HY-15922). PTZ-343 greatly increases the light output of the peroxidase-catalyzed luminol chemiluminescent oxidation reaction (>80%)[1][2].

体外研究
(In Vitro)

PTZ-343 behaves as electron transfer mediator, it reacts with HRP-II to release HRP and a enhance (PTZ-343) radical. The enhancer (PTZ-343) radical quickly oxidizes luminol anions to induce light emission[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

343.40

Formula

C15H14NNaO3S2
CAS 号

101199-38-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Ettore Marzocchi, et al. Chemiluminescent detection systems of horseradish peroxidase employing nucleophilic acylation catalysts. Anal Biochem. 2008 Jun 15;377(2):189-94.

    [2]. WenxiaZhang, et al. A novel electrochemical biomimetic sensor based on E-MIP artificial acceptor and SI-ATRP assisted signal amplification. Journal of Electroanalytical Chemistry. Volume 842, 1 June 2019, Pages 24-33

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