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Kurarinol (Synonyms: 苦参醇)
Kurarinol 是一种黄烷酮,在 Sophora flavescens 根中被发现。Kurarinol 是一种竞争性的酪氨酸酶 (tyrosinase) 抑制剂,对蘑菇型酪氨酸酶作用的 IC50 为 0.1 μM 。
Kurarinol Chemical Structure
CAS No. : 855746-98-4
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生物活性 |
Kurarinol is a flavanone found in the root of Sophora flavescens. Kurarinol is a competitive tyrosinase inhibitor, with IC50 of 0.1 μM for mushroom tyrosinase[1]. |
IC50 & Target |
IC50: 0.1 μM (mushroom tyrosinase)[1] |
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体外研究 (In Vitro) |
Kurarinol manifests relatively low cytotoxic activity (EC50>30 μM)[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Kurarinol (20 mg/kg; p.o.; daily; for 3 days) reduces serum lipid levels in high-Cholesterol diet induced hyperlipidemic rats[3]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
456.53 |
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Formula |
C26H32O7 |
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CAS 号 |
855746-98-4 |
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中文名称 |
苦参醇 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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