L-Azatyrosine

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

L-Azatyrosine 

L-Azatyrosine 是一种从 Streptomyces chibaensis 中分离出来的具有抗肿瘤活性的抗生素。L-Azatyrosine 可以使携带致癌 Ras 基因的转化细胞恢复正常的表型行为。

L-Azatyrosine

L-Azatyrosine Chemical Structure

CAS No. : 58525-82-9

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

生物活性

L-Azatyrosine is an antitumor antibiotic isolated from Streptomyces chibaensis. L-Azatyrosine can restore normal phenotypic behavior to transformed cells bearing oncogenic Ras genes[1][2].

分子量

182.18

Formula

C8H10N2O3
CAS 号

58525-82-9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Adamczyk M, et, al. Enantioselective synthesis of (2-pyridyl)alanines via catalytic hydrogenation and application to the synthesis of L-azatyrosine. Org Lett. 2001 Oct 4;3(20):3157-9.

    [2]. Shindo-Okada N, et, al. Permanent conversion of mouse and human cells transformed by activated ras or raf genes to apparently normal cells by treatment with the antibiotic azatyrosine. Mol Carcinog. 1989;2(3):159-67.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务