MAGE-3 (271-279)

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MAGE-3 (271-279) 

MAGE-3 (271-279) 是一个由 MAGE-3 编码的黑色素瘤抗原的 271-279 序列的短肽。MAGE-3 是一种 CTL 定义的 MAGE-3 蛋白,与人类白细胞抗原 (HLA)-A2 分子相关。MAGE-3 在包括恶性黑色素瘤在内的不同人类肿瘤类型中过表达,但在睾丸和胎盘以外的正常组织中没有过表达。

MAGE-3 (271-279)

MAGE-3 (271-279) Chemical Structure

CAS No. : 160295-81-8

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生物活性

MAGE-3 (271-279) is a 271-279 residue peptide derived from melanoma antigens encoded by MAGE-3. MAGE-3 is a cytolytic T lymphocyte (CTL)-defined MAGE-3 protein associated with the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is overexpressed in different human tumor types, including malignant melanoma, but not by normal tissues except for testis and placenta[1].

分子量

1058.28

Formula

C53H79N13O10

CAS 号

160295-81-8

Sequence

Phe-Leu-Trp-Gly-Pro-Arg-Ala-Leu-Val

Sequence Shortening

FLWGPRALV

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. J Herman, et al. A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3. Immunogenetics. 1996;43(6):377-83.

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