3-Methoxybenzamide(Synonyms: 3-MBA)

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3-Methoxybenzamide (Synonyms: 3-MBA)

3-Methoxybenzamide (3-MBA) 是 ADP-核糖转移酶 (ADPRTs) 和 PARP 的抑制剂，抑制枯草芽孢杆菌的细胞分裂，导致细胞最终裂解。3-Methoxybenzamide (3-MBA) 可促进蓝薯 (Solanum tuberosum L. subsp. andigenum) 植株的生长、微瘤化和转化效率。

3-Methoxybenzamide(Synonyms: 3-MBA)

3-Methoxybenzamide Chemical Structure

CAS No. : 5813-86-5

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生物活性

3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells[1]. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum)[2].

体外研究
(In Vitro)

3-Methoxybenzamide (0-30 mM) affects septation via the FtsZ system during both vegetative growth and sporulation[1].
3-Methoxybenzamide (3 MB; 0.2 to 0.6 mM) significantly increaseS the growth and microtuber formation of in vitro propagated plants[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: ftsZ mutant strains.
Concentration: 0-30 mM.
Incubation Time: 30℃ overnight.
Result: Changes directly or indirectly the ability of ftsZ to bind or hydrolyze the guanine nucleotide, ultimately leading to the inhibition of Zring formation.

分子量

151.16

Formula

C8H9NO2
CAS 号

5813-86-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Y Ohashi, et al. The lethal effect of a benzamide derivative, 3-methoxybenzamide, can be suppressed by mutations within a cell division gene, ftsZ, in Bacillus subtilis. J Bacteriol. 1999 Feb;181(4):1348-51.

    [2]. Venkateswari J. Chetty, et al. Poly (ADP-ribose) polymerase inhibitor 3-methoxybenzamide enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum). In Vitro Cellular & Developmental Biology – Plant (2020).

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