PUMA BH3 TFA | whatman (沃特曼)

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PUMA BH3 TFA

PUMA BH3 (TFA) 是一种 p53 正向凋亡调控因子 (PUMA) BH3 结构域多肽，作为 Bak 的直接激活剂，K_d 值为 26 nM。

PUMA BH3 TFA Chemical Structure

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生物活性

PUMA BH3 (TFA) is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a K_d of 26 nM^[1].

IC₅₀ & Target^[1]

Bak

26 nM (Kd)

分子量

3163.32

Formula

C₁₃₀H₂₀₃F₃N₄₂O₄₅S

Sequence Shortening

EEQWAREIGAQLRRMADDLNAQYER

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. Dai H, et al. Evaluation of the BH3-only protein Puma as a direct Bak activator. J Biol Chem. 2014 Jan 3;289(1):89-99.

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