E3 ligase Ligand 13

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E3 ligase Ligand 13 

E3 ligase Ligand 13 是一种 E3 泛素连接酶配体。E3 ligase Ligand 13 可以通过 linker 与靶蛋白配体连接，形成 PROTAC。PROTAC 可诱导促癌蛋白发生泛素化降解。

E3 ligase Ligand 13

E3 ligase Ligand 13 Chemical Structure

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1 g 询价
2 g 询价

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生物活性

E3 ligase Ligand 13 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 13 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

分子量

530.61

Formula

C31H34N2O6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

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