上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。
NLS-StAx-h
NLS-StAx-h 是选择性的 Wnt 信号传导的固定肽抑制剂，IC50 为 1.4 μM。NLS-StAx-h 有效抑制 β-catenin-转录因子的相互作用。NLS-StAx-h 抑制结直肠癌细胞的增殖和迁移。
NLS-StAx-h Chemical Structure
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| 100 μg | 询价 |
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| 生物活性 |
NLS-StAx-h is a selective, stapled peptide inhibitor of Wnt signaling with an IC50 of 1.4 μM. NLS-StAx-h efficiently inhibits β-catenin-transcription factor interactions. NLS-StAx-h inhibits proliferation and migration of colorectal cancer cells[1]. |
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| IC50 & Target[1] |
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| 体外研究 (In Vitro) |
NLS-StAx-h (10 μM, 72 hr) reduces the viability of both SW-480 and DLD-1 by more than 80%. NLS-StAx-h results in gene expression changes[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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| 分子量 |
3445.26 |
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| Formula |
C53H100N19O10V2W |
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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| 参考文献 |
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