LolCDE-IN-2

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

LolCDE-IN-2 

LolCDE-IN-2 是有效的 Lol 蛋白 (LolCDE) 抑制剂。LolCDE-IN-2 抑制 E. coli MG1655 的 MIC 值为 2 μg/ml。 具有抗菌活性。

LolCDE-IN-2

LolCDE-IN-2 Chemical Structure

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生物活性

LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 inhibits E. coli MG1655 with a MIC of 2 μg/ml. Antibacterial activity[1].

体外研究
(In Vitro)

The P. aeruginosa ΔlolCDE::CTX-lolCDEE. colistrain becomes more susceptible to LolCDE-IN-2 (compound 2A) when either the MexAB-OprM efflux pump is lacking or the permeability of its OM is increased by the expression of the FpvA-ΔP protein; in each case, these strains show an MIC of 16 µg/ml[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

367.40

Formula

C22H17N5O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Christian Lorenz, et al. Correct Sorting of Lipoproteins into the Inner and Outer Membranes of Pseudomonas aeruginosa by the Escherichia coli LolCDE Transport System. Molecular Biology and Physiology.

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