PTD-p65-P1 Peptide

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。

PTD-p65-P1 Peptide 

PTD-p65-P1 Peptide 是一种核转录因子 NF-kappaB 抑制剂,由一个 antennapedia 衍生的膜转运肽序列 (PTD) 连接 p65-P1 构成, 选择性地抑制由各种刺激诱导的 NF-kappaB 活性。

PTD-p65-P1 Peptide

PTD-p65-P1 Peptide Chemical Structure

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PTD-p65-P1 Peptide 的其他形式现货产品:

PTD-p65-P1 Peptide TFA

生物活性

PTD-p65-P1 Peptide is a nuclear transcription factor NF-kappaB inhibitor, composed of a membrane-translocating peptide sequence generated from antennapedia (PTD) conjugated with p65-P1, which selectively inhibits activation induced by various inflammatory stimuli[1].

IC50 & Target

NF-kappaB[1]

分子量

3829.50

Formula

C168H275N57O44S

Sequence Shortening

DRQIKIWFQNRRMKWKKQLRRPSDRELSE

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Takada Y, et al. Identification of a p65 peptide that selectively inhibits NF-kappa B activation induced by various inflammatory stimuli and its role in down-regulation of NF-kappaB-mediated gene expression and up-regulation of apoptosis. J Biol Chem. 2004 Apr 9;279(15):15096-104.

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