Heliotrine N-oxide

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Heliotrine N-oxide 

Heliotrine N-oxide 是 Heliotrine (HY-126128) 对应的吡咯利嗪生物碱类氮氧化物 (PA N-oxide)。Heliotrine N-oxide 可导致吡咯基 DNA 加合物 (DNA adduct) 的形成，并可能引发 PA 诱导的肝肿瘤的启动。

Heliotrine N-oxide

Heliotrine N-oxide Chemical Structure

CAS No. : 6209-65-0

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生物活性

Heliotrine N-oxide is the corresponding PA (pyrrolizidine alkaloid) N-oxide of Heliotrine (HY-126128). Heliotrine N-oxide leads to the formation of pyrrolic DNA adducts and potential initiation of PA-induced liver tumors in vivo[1].

体外研究
(In Vitro)

DNA adduct is a segment of DNA bound to a cancer-causing chemical. This process could be the start of a cancerous cell, or carcinogenesis.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

329.39

Formula

C16H27NO6
CAS 号

6209-65-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Xiaobo He, et al. Pyrrolizidine alkaloid-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides. J Food Drug Anal. 2017 Oct;25(4):984-991.

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