上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白,专注于信号通路和疾病研究领域。
Raloxifene (Synonyms: Keoxifene; LY156758 free base; LY139481)
Raloxifene (Keoxifene) 是一种苯并噻吩类选择性雌激素受体 (estrogen receptor) 调节剂 (SERM),对骨、血脂有雌激素激动作用,对乳腺和子宫有雌激素拮抗作用。Raloxifene 用于乳腺癌和骨质疏松症研究。
Raloxifene Chemical Structure
CAS No. : 84449-90-1
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Raloxifene 的其他形式现货产品:
生物活性 |
Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[1]. |
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IC50 & Target |
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体内研究 (In Vivo) |
Raloxifene (4 mg/kg; intragastrically; daily for 13 weeks) significantly prevents bone loss in ovariectomized (OVX) rats[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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Clinical Trial |
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分子量 |
473.58 |
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Formula |
C28H27NO4S |
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CAS 号 |
84449-90-1 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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参考文献 |
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