Ganglioside GD3 disodium salt

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Ganglioside GD3 disodium salt 

Ganglioside GD3 disodium salt 是一种黑色素相关抗原，可用作黑色素瘤免疫的研究。

Ganglioside GD3 disodium salt

Ganglioside GD3 disodium salt Chemical Structure

CAS No. : 497932-19-1

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生物活性

Ganglioside GD3 disodium salt is a melanoma-associated antigen and has been used as a target for the immune therapy of melanomas[1].

体外研究
(In Vitro)

Ganglioside GD3 is highly expressed in melanomas in comparison with melanocytes, is exclusively expressed in the early developmental stage of the fetal brain, and is highly expressed in activated T lymphocytes and in T cell malignant tumor cells suggest that GD3 is involved in tumor phenotypes, such as enhanced proliferation and frequent metastasis[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1516.71

Formula

C70H123N3Na2O29
CAS 号

497932-19-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Kazunori Hamamura, et al. Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. Proc Natl Acad Sci U S A. 2005 Aug 2;102(31):11041-6.

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