Podophyllotoxone

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Podophyllotoxone 

Podophyllotoxone 是从八角莲根中分离得到的，具有抗癌活性。Podophyllotoxone 能够抑制 tubulin 微管蛋白聚合。

Podophyllotoxone

Podophyllotoxone Chemical Structure

CAS No. : 477-49-6

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生物活性

Podophyllotoxone is isolated from the roots of Dysosma versipellis and has anti-cancer activities.Podophyllotoxone is able to inhibit the tubulin polymerization[1].

IC50 & Target

Microtubule/Tubulin[1]
体外研究
(In Vitro)

Podophyllotoxone inhibits human prostate cancer cells PC3 and DU145 growth with IC50 values of 14.7 and 20.6 µM[1].

上海金畔生物科技有限公司 has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

412.39

Formula

C22H20O8
CAS 号

477-49-6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Juan Li , et al. Absolute Configuration of Podophyllotoxone and Its Inhibitory Activity Against Human Prostate Cancer Cells. Chin J Nat Med. 2015 Jan;13(1):59-64.

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