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AV-153
AV-153 是一种 1,4-dihydropyridine (1,4-DHP) 衍生物,具有抗突变作用。在体外人细胞内,AV-153 可以插入到 DNA 的单链断裂处,减少 DNA 损伤并刺激 DNA 修复。AV-153 可以与胸腺嘧啶和胞嘧啶相互作用,对聚 (ADP) 核糖基化有影响。AV-153 具有抗癌活性。
AV-153 Chemical Structure
CAS No. : 27296-05-5
规格 | 是否有货 | ||
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100 mg | 询价 | ||
250 mg | 询价 | ||
500 mg | 询价 |
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AV-153 的其他形式现货产品:
生物活性 |
AV-153, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 has anti-cancer activity[1][2][3]. |
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体外研究 (In Vitro) |
AV-153 causes IC50s for Raji and HL-60 cells of 14.9 mM and 10.3 mM, respectively[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
319.29 |
Formula |
C14H18NNaO6 |
CAS 号 |
27296-05-5 |
运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |
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