Boc-NH-PEG8-CH2CH2COOH

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Boc-NH-PEG8-CH2CH2COOH 

Boc-NH-PEG8-CH2CH2COOH 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Boc-NH-PEG8-CH2CH2COOH

Boc-NH-PEG8-CH2CH2COOH Chemical Structure

CAS No. : 1334169-93-5

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生物活性

Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

541.63

Formula

C24H47NO12
CAS 号

1334169-93-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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