Gly-Gly-Gly-PEG4-DBCO

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Gly-Gly-Gly-PEG4-DBCO 

Gly-Gly-Gly-PEG4-DBCO 是一种可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

Gly-Gly-Gly-PEG4-DBCO

Gly-Gly-Gly-PEG4-DBCO Chemical Structure

CAS No. : 2353409-80-8

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生物活性

Gly-Gly-Gly-PEG4-DBCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

694.77

Formula

C35H46N6O9
CAS 号

2353409-80-8
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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