2-Hydroxyethyl disulfide mono-tosylate

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2-Hydroxyethyl disulfide mono-tosylate 

2-Hydroxyethyl disulfide mono-tosylate 是一种可降解 (cleavable) 的 ADC linker，可用于合成抗体偶联药物 (ADC)。

2-Hydroxyethyl disulfide mono-tosylate

2-Hydroxyethyl disulfide mono-tosylate Chemical Structure

CAS No. : 1807530-16-0

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生物活性

2-Hydroxyethyl disulfide mono-tosylate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Cleavable

 

体外研究
(In Vitro)

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

308.44

Formula

C11H16O4S3
CAS 号

1807530-16-0
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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