Amino-PEG2-C2-hydrazide-Boc

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Amino-PEG2-C2-hydrazide-Boc 

Amino-PEG2-C2-hydrazide-Boc 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Amino-PEG2-C2-hydrazide-Boc

Amino-PEG2-C2-hydrazide-Boc Chemical Structure

CAS No. : 2100306-60-1

规格 是否有货
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生物活性

Amino-PEG2-C2-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

291.34

Formula

C12H25N3O5
CAS 号

2100306-60-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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