N-Boc-N-bis(PEG4-NHS ester) | whatman (沃特曼)

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N-Boc-N-bis(PEG4-NHS ester)

N-Boc-N-bis(PEG4-NHS ester) 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

N-Boc-N-bis(PEG4-NHS ester) Chemical Structure

CAS No. : 2093153-08-1

规格		是否有货
100 mg		询价
250 mg		询价
500 mg		询价

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生物活性

N-Boc-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs	Alkyl/ether

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

807.84

Formula

C₃₅H₅₇N₃O₁₈

CAS 号

2093153-08-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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