m-PEG4-azide(Synonyms: 13-Azido-2,5,8,11-tetraoxatridecane)

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m-PEG4-azide (Synonyms: 13-Azido-2,5,8,11-tetraoxatridecane)

m-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC。

m-PEG4-azide(Synonyms: 13-Azido-2,5,8,11-tetraoxatridecane)

m-PEG4-azide Chemical Structure

CAS No. : 606130-90-9

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生物活性

m-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

233.26

Formula

C9H19N3O4

CAS 号

606130-90-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献
  • [1]. Belen Begines, et al. Synthesis of Reduction Sensitive Comb-Like Polyurethanes Using Click Chemistry. Journal of Polymer Science Part A: Polymer Chemistry, 2016, 54(24), 3888-3900.

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