Boc-aminooxy-PEG1-propargyl

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Boc-aminooxy-PEG1-propargyl 

Boc-aminooxy-PEG1-propargyl 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。

Boc-aminooxy-PEG1-propargyl

Boc-aminooxy-PEG1-propargyl Chemical Structure

CAS No. : 1895922-72-1

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生物活性

Boc-aminooxy-PEG1-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

215.25

Formula

C10H17NO4
CAS 号

1895922-72-1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

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