Ald-CH2-PEG3-CH2-Boc

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Ald-CH2-PEG3-CH2-Boc 

Ald-CH2-PEG3-CH2-Boc是一种 PROTAC linker,属于 PEGAlkyl/ether 类,可以用于合成 SGK3 激酶 PROTAC 降解剂。

Ald-CH2-PEG3-CH2-Boc

Ald-CH2-PEG3-CH2-Boc Chemical Structure

CAS No. : 2100306-54-3

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生物活性

Ald-CH2-PEG3-CH2-Boc is a PEG– and Alkyl/ether-based PROTAC linker can be used in the synthesis of SGK3 kinase PROTAC degrader[1].

IC50 & Target

PEGs

 

Alkyl/ether

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

306.35

Formula

C14H26O7

CAS 号

2100306-54-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034.

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