Propargyl-PEG3-CH2COOH

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白，专注于信号通路和疾病研究领域。

Propargyl-PEG3-CH2COOH  纯度: ≥98.0%

Propargyl-PEG3-CH2COOH 是一种 PROTAC linker，属于 PEG 类。Propargyl-PEG3-CH2COOH 可用于合成一系列 PROTAC 分子。

Propargyl-PEG3-CH2COOH

Propargyl-PEG3-CH2COOH Chemical Structure

CAS No. : 1694731-93-5

规格 价格 是否有货 数量
50 mg ￥1800 In-stock
100 mg ￥2800 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Propargyl-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

246.26

Formula

C11H18O6
CAS 号

1694731-93-5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献

  • [1]. Wurz RP, et al. A “Click Chemistry Platform” for the Rapid Synthesis of Bispecific Molecules for Inducing ProteinDegradation. J Med Chem. 2018 Jan 25;61(2):453-461.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务